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Colloquium - 8 Mar 2001

Department of Statistics
Texas A&M University

STATISTICS COLLOQUIUM

DEPARTMENT OF STATISTICS
and
CENTER FOR ENVIRONMENTAL AND RURAL HEALTH STATISTICS
Texas A&M University

Yigian (Eugene) Hwang

Assistant Member
Division of Public Health Sciences
Fred Hutchinson Cancer Research Center

Consistent Functional Methods for Logistic
Regression with Errors in Covariates

ABSTRACT: We propose consistent functional methods for logistic regression in which some covariates are not accurately ascertainable. Among existing methods for generalized linear models, the conditional-score approach to normal errors does not guarantee the convergence of its estimators, and the corrected-score method is generally not applicable to the logistic-regression score function. In this talk, after constructing a correction-amenable estimation procedure with the true covariates, we formulate parametric- and nonparametric-correction estimation procedures in the presence of additive errors in covariates. The former procedure accommodates the situation with known (but not necessarily normal) error distribution, whereas the latter further relieves this distributional assumption requirement given that additional replicated mismeasured covariates or instrumental variables are available. Large-sample theory is developed; the proposed estimators are consistent and asymptotically normal. We investigate their asymptotic relative efficiency and, through simulations, examine their finite-sample properties. Application to an AIDS study is provided to illustrate the proposed methods.

Joint work with C. Y. Wang.

DATE:  Thursday, March 8, 2001
TIME:  4:00 p.m.-5:00 p.m.
PLACE:  Room 150, Blocker

Refreshments will be served in the Blocker Building, Room 447, at 3:30 p.m.


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